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miRNAs

网络核糖核酸；微小核糖核酸；微核醣核酸

miRNAs

miRNAs

miRNAs

核糖核酸

微核糖核酸(miRNAs)是小片段不会转译出蛋白质的核糖核酸(RNA)，透过转译的抑制(translation inhibition)或传讯核糖核酸(mR…

微小核糖核酸

微小核糖核酸(miRNAs)是一类新发现的蛋白非编码核糖核酸,由19-23核苷酸组成,通过与其下游靶基因微小核糖核酸的3’端非翻 …

微核醣核酸

1.10 微核醣核酸(MIRNAS) - 12 - 1.11 与海马相关之疾病 - 12 - 1.12 研究目的 - 13 - 1.13论文架构 - 14 - 第二章　研究架构与方法 ...

1

It is unknown how much translational control is exerted by miRNAs on a genome -wide scale .

在基因组水平，哪些转录是由微 RNA 调控的还不为人知。

2

3

The few miRNAs that have been fully characterized were found in Caenorhabditis elegans and are required for development .

为数不多的微 RNA 已充分的特点中发现秀丽隐杆线虫和所需要的发展。

4

A subgroup of 6 miRNAs was able to distinguish long-term survivors with node -positive disease from those dying within 24 months.

亚组 6 个微 RNA 序列可鉴别淋巴结阳性胰腺癌长期存活患者与 2 年内死亡患者。

5

Virally encoded microRNAs (miRNAs) have recently been discovered in herpesviruses. However , their biological roles are mostly unknown .

最近发现了单纯疱疹病毒编码的小 RNA ，但它们的生物学作用几乎未知。

6

Although first discovered in C. elegans, miRNAs have since been shown to be involved in human cancers 5.

虽然最早在线虫体内发现，但已经证明，microRNA 能参与人类癌症的发生。

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Furthermore , miRNAs are continuously being shown to act as both oncogenes and tumor suppressors 5.

此外，microRNA 基因还不断被证实扮演着原癌基因和抑癌基因的角色。

8

More recent research has shown that miRNAs also play an important role in cancer .

最近的研究已经表明 miRNA 也在癌症中发挥重要作用。

9

Scientists have now identified more than 470 different miRNAs in humans .

科学家们目前已经在人体内发现了 470 多种不同的 miRNA 。

10

Many miRNAs are well conserved across species , suggesting an important role for them .

许多 microRNA 在不同物种间非常保守，暗示了它们的重要地位。

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