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TRPV1

TRPV1

TRPV1

TRPV1

1

Scientists have long known that the nervous system receptor known as TRPV1 can affect sensations of pain in the body .

科学家一直知道神经系统受体如已知的 TRPV1 能影响机体的疼痛感觉。

2

The team found that this compound activated TRPV1 channels - which alone triggered long-term depression in the brain tissue .

她的团队发现这个成分激活 TRPV1 通道，它可以独自激发脑组织的长时程抑郁。

3

Study on role of TRPV1 and its mechanisms will help us to understand pain physiology and to develop new analgesic drugs .

深入研究 TRPV1 的作用机制，有助于理解痛觉生理和开发新型镇痛药物。

5

Pain relief occurs after what is thought to be a reduction in TRPV1-expressing nociceptive nerve endings .

疼痛缓解后发生了被认为是在 TRPV1 受体，表达痛觉神经末梢减少。

6

When scientists discovered that the VR1 receptor was a member of the larger family of TRP ion channels , the VR1 receptor was renamed TRPV1.

科学家们发现 VR1 受体是瞬时受体电位通道（TRPionchannels ）家族的一员，于是 VR1 受体又被命名为 TRPV1 。

7

TRPV1 can detect noxious stimulus and convert it into action potentials traveling to the central and forming pain sensation .

TRPV1 能够感受伤害性刺激，将之转化为动作电位，传至中枢形成痛觉。

9

Further , rimonabant entirely blocked long-term depression by blocking TRPV1 channels .

另外，利莫那班通过阻断 TRPV1 通道完全阻断长时程抑郁。

10

When TRPV1 is activated or sensitized by proton , bradykinin , or endovanilloids released during myocardial ischemia (MI), it leads to angina .

心肌缺血时释放的质子，缓激肽，或内源性香草酸均能激动或致敏 TRPV1 ，导致心绞痛。

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