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曲林晶

曲林晶

曲林晶

曲林晶

1

Sertraline hydrochloride Forms V and VI may be produced from either sertraline hydrochloride or sertraline base by crystallization .

盐酸舍曲林晶形 V 和 VI 可通过结晶由盐酸舍曲林或舍曲林碱来制备。

2

It also discloses the components of crystal II containing sertraline -hydrochloride and the use of these drugs .

也公开了含有盐酸舍曲林晶形 II 的药物组合物，和应用上述药物组合物治疗的方法。

3

Accordnig to the present invention , sertraline hydrochloride Form II may be produced directly for sertraline base or sertraline mandelate.

根据本发明，盐酸舍曲林晶形 II 可直接由舍曲林碱或扁桃酸舍曲林制备。

4

According to the present invention , sertraline hydrochloride form III may be produced by heating sertraline hydrochloride Forms V and VI.

根据本发明，盐酸舍曲林晶形 III 可通过加热盐酸舍曲林晶形 V 和 VI 来制备。

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