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诺福韦

网络tenofovir

诺福韦

诺福韦

诺福韦

tenofovir

E.特诺福韦 (tenofovir) ：抗病毒剂，艾滋病治疗。世界范围多国上市，广泛注册。

1

He said the current oral use of tenofovir is highly effective and safe , and that tenofovir microbicide differs from previous microbicides .

他说当前口服替诺福韦是高度有效且安全的，而且替诺福韦杀微生物剂不同于此前的杀微生物剂。

2

According to Gilead, tenofovir has no known effect against the herpes virus , HSV2, so how the gel worked against that virus is unknown .

Gilead 公司称，泰诺福韦未发现有预防感染疱疹病毒（HSV2 ）的效果，所以这种凝胶是如何保护人体免受疱疹病毒感染的仍属未知。

3

His HBsAg was detectable , and he was started on tenofovir (TDF) at the time of this abstract submission .

他的乙肝表面抗原检测，并在本提交论文摘要时，他开始替诺福韦（TDF ）。

4

The single dose of oral tenofovir did not provide any protection against HIV in rectal tissue samples.

在单剂量口服泰诺福韦没有提供任何抗击艾滋病毒在直肠癌组织中的保护。

5

This would be one of the class B drugs (telbivudine or tenofovir) hopefully or lamivudine .

应该选用 B 级药物（替比夫定或替诺福韦）或拉米夫定。

6

Tenofovir gel is a third generation microbicide and is unique in that it works within cells to stop HIV from replicating .

替诺福韦凝胶是第三代杀微生物剂，而且它在细胞内部阻止艾滋病病毒复制的方式是独特的。

7

Administered as a pill in drug combinations, the drug is widely used to treat people already infected with the AIDS virus .

泰诺福韦这种复方药物是一种丸剂，被广泛用于治疗已感染艾滋病毒的人。

8

The trial directly compared the anti-HIV activity of a single dose of oral tenofovir to a single dose of rectally-applied tenofovir gel .

该试验直接比较了单剂量口服泰诺福韦抗艾滋病毒活性的直肠，单剂量应用泰诺福韦凝胶。

9

This was followed by six days of at-home dosing of tenofovir gel or a placebo gel , with the last and seventh dose given in the clinic .

其次是在六，泰诺福韦凝胶或安慰剂凝胶剂量家诊所在给定的最后一个，第七剂量，天。

10

The small amounts of tenofovir (found in breast milk in animal studies) are very unlikely to cause viral resistance , they wrote.

泰诺福韦（在乳房在动物实验中发现牛奶）少量不太可能导致病毒抵抗，他们写道。

11

Tenofovir only needs to be taken once a day , and might even provide protection if some doses were missed .

替诺福韦只需要每天服用一次，并且即使偶尔漏服也能提供保护。

12

So , with telbivudine, if someone is not negative at 6 months or less, they need also to have add-on adefovir or tenofovir.

因此，对于替比夫定，如果用药 6个月或更短时间患者 HBVDNA 仍未转阴，也需要加用阿德福韦酯或替诺福韦。

14

15

Some opposed tenofovir's use in a microbicide because they worried that it would encourage the emergence of such resistance.

一些人反对在杀菌剂中使用替诺福韦，因为他们担心这或许会助长生成这种抗体。

21

22

Unlike other gels , which have failed , tenofovir is not active on the skin 's surface .

与其他失败了的凝胶不同，替诺福韦在皮肤表面上不会起作用。

23

25

The next study that I want to discuss is a study comparing tenofovir vs tenofovir and emtricitabine in adefovir-experienced patients .

接下来的学习，我想讨论的是一个比较研究阿德福韦的患者替诺福韦与替诺福韦和恩曲他滨。

26

27

Tenofovir is registered with the Hospital Authority , and each tablet costs HK$86 .

泰诺福韦登记与医院管理局，每片费用港币 86 元。

28

That has been demonstrated already for lamivudine and it is the same for drugs like entecavir or entecavir.

拉米夫定的应用已经证明了这一点，替诺福韦与恩替卡韦同样是这样。

30

Would more than 1 percent tenofovir in the gel, or a two-drug mix , work better?

凝胶中是添加超过 1%的泰诺福韦，还是混合两种药物的效果更好？

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