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去乙酰

网络De-acetylation; deacylated

去乙酰

去乙酰

去乙酰

De-acetylation

...异功能」（遗传密码／基因）关闭掉。这两把锁，一把叫去乙酰（De-acetylation），另一把叫重甲基（Hyper- methylation） …

deacylated

...osphotidic acid，此又可转变为磷脂或去乙酰（deacylated）而生成花生四烯酸（arachidonic），Ca

1

He described himself as standing in the middle , but hopeful that the stirring would turn out to be "key modulators of aging . "

他称自己是一个中立者，但他对去乙酰化酶终将成为 “老化的关键调节器 ”这一前景充满信心。

4

Sirtuins are key regulators of clinically important cellular and organismal processes including metabolism, cell division and aging .

去乙酰化酶是临床上常见的关键调节细胞和器官流程，包括代谢、细胞分裂和老化。

5

Objective : To improve the synthetic procedure of the histone deacetylase (HDAC) inhibitor SAHA.

目的：改进组蛋白去乙酰化酶抑制剂 SAHA 的合成工艺。

6

The significance of sirtuin-dependent regulation of homeostasis with respect to diverse biological organisms will be discussed .

去乙酰化酶依靠规定的意义的心智就多样的生物有机体，将会被讨论。

7

HDAC inhibitors block the removal of these acetyl groups.

HDAC 抑制剂阻断了去乙酰基化过程。

10

The good news clinically, said Munster, is that several existing compounds known as histone deacetylase inhibitorsdirectly target AKT.

Munster 说，好消息是被称为组蛋白去乙酰酶抑制剂的几个现有化合物的直接靶标就是 AKT 。

11

But the credibility of SRT-1720 and its cousins also rests on their design as sirtuin activators .

但是 SRT-1720 及其类似药物可信度同样依赖于其去乙酰化酶激活剂的身份。

12

Histones are proteins that regulate DNA packing , and histone deacetylases are enzymes that control the way those proteins work .

组蛋白是管理 DNA 装壳的蛋白质，组蛋白去乙酰酶是控制这些蛋白质工作的催化剂。

13

ObjectiveTo investigate the antitumor effect of MS275, a histone deacetylase inhibitor, on growth of the human myeloma cell line U266.

目的研究组蛋白去乙酰化酶抑制剂 MS275 对人多发性骨髓瘤细胞 U266 增殖的影响。

14

First , AOF1 does not appear to form stable protein complexes containing histone deacetylases.

首先，AOF1 不与组蛋白去乙酰化酶共同形成稳定的复合体；

15

Advances in pharmacological study of histone deacetylase inhibitors

组蛋白去乙酰酶抑制剂的药理学研究进展

17

Advances in combination therapies of histone deacetylase inhibitors with other antitumor agents

组蛋白去乙酰酶抑制剂联合应用治疗肿瘤的研究进展

18

Studies on the Membrane - formed Property of Denatured Konjac Glucomannan by De - acetylation

魔芋葡甘露聚糖去乙酰基改性制膜特性研究

19

Structure based virtual screening of HDAC inhibitors

基于结构的组蛋白去乙酰化酶抑制剂虚拟筛选

20

A new target of cancer therapy : advances in the study of histone deacetylase

抗肿瘤药物新靶点：组蛋白去乙酰酶的研究进展

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